Stochastic resonance as a collective property of ion channel assemblies
نویسندگان
چکیده
منابع مشابه
Stochastic resonance as a collective property of ion channel assemblies
By use of a stochastic generalization of the Hodgkin-Huxley model we investigate both the phenomena of stochastic resonance (SR) and coherence resonance (CR) in variable size patches of an excitable cell membrane. Our focus is on the challenge how internal noise stemming from individual ion channels does affect collective properties of the whole ensemble. We investigate both an unperturbed situ...
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We consider the statistical properties of action potentials generated by clusters of sodium and potassium channels due to channel noise and/or external stimulation. Since the fluctuations are related to the cluster size, a size-resonance effect — analog to stochastic resonance — is observed that facilitates optimal decoding of small external stimuli at optimal cluster sizes. Furthermore, in ana...
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The behaviour of a system of ion channels formed across the cell membrane is presented. The infinite number of channels with an infinite coupling is introduced first as a reference point for the detailed derivation of the thermal-equilibrium probability distribution and the classification of the phase transitions. Fluctuations in a finite system are discussed next. We propose a new, step-like m...
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Stochastic models of ion channel gating date back as far as the pioneering work of Hodgkin and Huxley (1952), whose gating variables are often interpreted as probabilities. Sakmann and Neher directed the efforts that led to the first single-channel recordings, for which they won the Nobel Prize in Physiology and Medicine in 1991. Single-channel recordings (Sakmann and Neher, 1995) demonstrate t...
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ژورنال
عنوان ژورنال: Europhysics Letters (EPL)
سال: 2001
ISSN: 0295-5075,1286-4854
DOI: 10.1209/epl/i2001-00482-6